https://www.ceesdekker.net - An Overview
https://www.ceesdekker.net - An Overview
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Spatial framework facilitates cooperation in a very social Predicament: empirical proof from the bacterial Group
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I can rarely visualize how I, to be a geneticist, would have the ability to learn fundamental physics, not to mention contend at the very best. How did you go about it?
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt in excess of het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft satisfied veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
Within the years following these discoveries, my investigate pursuits shifted to biophysics and nanobiology, and I became less linked to the event of nanotube electronics. The main focus of many scientists in the sector also shifted to graphene (exactly where, funnily sufficient, the first graphene ribbons were called ‘nanotubes which might be Reduce open up together their size’) following the invention of the two-dimensional material in 2004.
Considering that 2000 he moved to solitary-molecule biophysics and nanobiology, with research from DNA supercoiling studies of nucleosomes and DNA maintenance proteins to DNA translocation by way of nanopores. Just lately his analysis has centered on learning mobile division with micro organism on chip, although his greatest desire is while in the path of knowing artificial cells.
Move-driven rotary motors like windmills and drinking water wheels push ceesdekker.net purposeful procedures in human society. Even though examples of these kinds of rotary motors also aspect prominently in mobile biology, their synthetic construction on the nanoscale has remained complicated. Here we demonstrate movement-driven rotary motion of a self-organized DNA nanostructure which is docked on to a nanopore in a thin reliable-condition membrane. An elastic DNA bundle self-assembles right into a chiral conformation on phoretic docking onto the reliable-condition nanopore, and subsequently displays a sustained unidirectional rotary motion of up to 20 rev s−1.
‘You shouldn't just consider the queries of tomorrow, and also evaluate the thoughts of your working day just after tomorrow’
Pretty great, but that wasn’t seriously exactly where my fascination lay. I needed to pioneer and I had the sensation which was no longer attainable, as the most interesting basic insights experienced now been uncovered. But my area had formulated many fascinating new instruments to evaluate individual molecules. I decided that I wished to utilize this to biology, to look at it from a Bodily viewpoint.’
In 1993 he was appointed as Associate Professor at Delft University of Know-how. Within the mid-nineties Dekker and his workforce accomplished accomplishment with the invention of the electronic Houses of carbon nanotubes, the main single-molecule transistor together with other nanoscience.
‘That worries the artificial cell, as Element of the Dutch BaSyC initiative. Craig Venter seemed major-down in Individuals times and identified about five hundred genes that happen to be minimally needed for the functioning cell. We wish to look bottom-up: how can we shift from a handful of molecules to an entire Organic program?
Permit’s initially glimpse again in the meanwhile any time you made a decision to change your concentration from superconductivity and nanotubes to biology at the conclusion of the nineteen nineties.
2004, discovery of latest physics in translocation of DNA through nanopores; to start with experimental examine of ions conduction in nanofluidic channels; initial electrochemistry with individual solitary-wall carbon nanotubes; STM detection and control of phonons in carbon nanotubes; to start with electrical docking of microtubules on kinesin-coated nanostructures; 1st biophysics characterization of the mechanical Attributes of double-stranded RNA; and very first one-molecule examine of DNA translocation by a restriction-modification enzyme.